Photochemical, Pd-Catalyzed Activation of Alkyl Bromides and Chlorides for Alkylative Cascade Cyclization of <i>O</i> -Cyano Acrylamides
-cyano acrylamides has been developed as a route toward phenanthridines. The reaction involves readily available, unfunctionalized alkyl bromides and chlorides and has also been demonstrated with bromobenzene. The key features of this transformation are the use of a simple catalytic system, activation of a wide variety of bromo- and chloroalkanes, and expeditious reactivity under mild conditions.
Authors
- Kirti Khanna (ORCID: https://orcid.org/0000-0002-0093-9451)
- Seshadri Reddy Nasireddy
- Shreya Sharma (ORCID: https://orcid.org/0000-0002-7527-8993)
- Anand Singh
- Aarti Mehra
Institutions
- Centre for Sustainable Energy (GB)
- Indian Institute of Technology Kanpur (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1021/acs.joc.6c00246
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Indian Institute of Technology Kanpur
- Ministry of Education, India
- Science and Engineering Research Board