Engineered <i>Bacillus subtilis</i> Systems for the Characterization and Detection of Peptide-Based Quorum Sensing in Gram-Positive Bacteria

strains to function as biosensors to detect the native AIPs of bacteria and produce a targeted antibiotic in response. These engineered systems should find utility for the study of QS in a range of fundamental and applied contexts.

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Publication Details

Journal
Biochemistry
Published
2026-04-15
DOI
https://doi.org/10.1021/acs.biochem.6c00065
Primary Topic
Bacterial biofilms and quorum sensing
Type
article
Field-Weighted Citation Impact
0.00

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article

Engineered Bacillus subtilis Systems for the Characterization and Detection of Peptide-Based Quorum Sensing in Gram-Positive Bacteria

A. Appel, Emma L. Eisenbraun, Helen E. Blackwell, Troy D. Vulpis et al.
Biochemistry
Bacterial biofilms and quorum sensing
article

Engineered Bacillus subtilis Systems for the Characterization and Detection of Peptide-Based Quorum Sensing in Gram-Positive Bacteria

A. Appel, Emma L. Eisenbraun, Helen E. Blackwell, Troy D. Vulpis, Alese M. Nelson, Brendan N. Prosser, Natalie L. Beebe
article en

Abstract

strains to function as biosensors to detect the native AIPs of bacteria and produce a targeted antibiotic in response. These engineered systems should find utility for the study of QS in a range of fundamental and applied contexts.

BiochemistryVol. 65(9)
University of Wisconsin–Madison (US)
Division of Chemistry
Zero hunger
Openalex Percentile: Top 27%
Bacterial biofilms and quorum sensing
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