Liver Transplantation as a Salvage Therapy Option in Colorectal Liver Metastases: Feasibility, Oncologic Outcomes, and Survival After Failure of Conventional Therapy—A Systematic Review and Meta-Analysis
In highly selected patients with unresectable colorectal liver metastases, liver transplantation is associated with favorable long-term survival despite frequent recurrence. Outcomes appear to be primarily driven by tumor biology rather than tumor burden, supporting the cautious use within specialized centers under structured selection protocols.
Authors
- Mehwish Ansar
- Rabia Arshad (ORCID: https://orcid.org/0000-0001-7654-3456)
- Tehreem Kazmi
- Faiza H Soomro
- Gulla Aiste
- Nadia Gulnaz (ORCID: https://orcid.org/0009-0007-8641-6478)
Institutions
- Vilnius University (LT)
- Divisional Headquarters Teaching Hospital Mirpur (PK)
- Shrewsbury and Telford Hospital NHS Trust (GB)
- Mid Yorkshire Hospitals NHS Trust (GB)
Publication Details
- Journal
- Cancers
- Published
- 2026-04-15
- DOI
- https://doi.org/10.3390/cancers18081254
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00