Cadmium chloride and erectile dysfunction: integrative evidence from network toxicology, Mendelian randomization, and in vitro validation
Background: ) and erectile dysfunction (ED), and to explore the underlying molecular mechanisms. Methods: on human umbilical vein endothelial cells (HUVECs), focusing on alterations in cell viability and gene expression. Results: expression. Conclusion: related signaling.
Authors
- Tao Zhou (ORCID: https://orcid.org/0000-0002-9782-7324)
- Chunyang Meng
- Yang Zeng (ORCID: https://orcid.org/0009-0000-4133-4080)
- Qingfu Deng
- Qilong Wu
- Yuqi Li
- Xinyao Zhu
- Jihong Wang
- Zhiyu Liu
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-04-15
- DOI
- https://doi.org/10.3389/fendo.2026.1798494
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Luzhou Science and Technology Bureau