Serum NOS1AP concentration: association with clinical schizophrenia polymorphism and metabolic syndrome

OBJECTIVE: To study the associations of the serum concentration of NOS1AP (Nitric Oxide Synthase 1 Adaptor Protein) with clinical polymorphism and components of metabolic syndrome (MS) in patients with schizophrenia. MATERIAL AND METHODS: <0.05. RESULTS: =0.043). There were no statistically significant differences in NOS1AP levels depending on the presence of hypertension or dyslipidemia. CONCLUSION: The found patterns suggest a common pathophysiological mechanism mediated by NOS1AP linking psychopathology to metabolic disorders.

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Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2026-04-15
DOI
https://doi.org/10.17116/jnevro2026126031167
Primary Topic
Tryptophan and brain disorders
Type
article
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article

Serum NOS1AP concentration: association with clinical schizophrenia polymorphism and metabolic syndrome

Elena G. Kornetova, Svetlana А. Ivanova, Д.А. Петкун, I. A. Mednova et al.
S S Korsakov Journal of Neurology and Psychiatry
Tryptophan and brain disorders
article

Serum NOS1AP concentration: association with clinical schizophrenia polymorphism and metabolic syndrome

Elena G. Kornetova, Svetlana А. Ivanova, Д.А. Петкун, I. A. Mednova, Y.V. Shternis
article en

Abstract

OBJECTIVE: To study the associations of the serum concentration of NOS1AP (Nitric Oxide Synthase 1 Adaptor Protein) with clinical polymorphism and components of metabolic syndrome (MS) in patients with schizophrenia. MATERIAL AND METHODS: <0.05. RESULTS: =0.043). There were no statistically significant differences in NOS1AP levels depending on the presence of hypertension or dyslipidemia. CONCLUSION: The found patterns suggest a common pathophysiological mechanism mediated by NOS1AP linking psychopathology to metabolic disorders.

S S Korsakov Journal of Neurology and PsychiatryVol. 126(3)
Siberian State Medical University (RU), Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences (RU), Tomsk National Research Medical Center (RU)
Good health and well-being
Openalex Percentile: Top 18%
Tryptophan and brain disorders
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Serum NOS1AP concentration: association with clinical schizophrenia polymorphism and metabolic syndrome — Elena G. Kornetova, Svetlana А. Ivanova, et al. · S S Korsakov Journal of Neurology and Psychiatry (2026) | TGRS Research Map | TGRS