Venous Thromboembolism and Gut Dysbiosis: Mechanistic Links Between Endotoxemia, Microbial Metabolites, and Thromboinflammation

The gut microbiome-VTE axis is biologically plausible and supported mainly by mechanistic and indirect evidence, but current data are insufficient to support strong causal conclusions. Further longitudinal, well-phenotyped, mechanistically informed studies are needed to determine whether microbiome-related pathways have measurable clinical relevance in human VTE.

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Publication Details

Journal
Nutrients
Published
2026-04-14
DOI
https://doi.org/10.3390/nu18081231
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Venous Thromboembolism and Gut Dysbiosis: Mechanistic Links Between Endotoxemia, Microbial Metabolites, and Thromboinflammation

Agata Stanek, Leon Smółka, Bartosz Pomianowski, Karolina Blady et al.
Nutrients
Gut microbiota and health
article

Venous Thromboembolism and Gut Dysbiosis: Mechanistic Links Between Endotoxemia, Microbial Metabolites, and Thromboinflammation

Agata Stanek, Leon Smółka, Bartosz Pomianowski, Karolina Blady, Karolina Kursa, Miłosz Strugała
article en

Abstract

The gut microbiome-VTE axis is biologically plausible and supported mainly by mechanistic and indirect evidence, but current data are insufficient to support strong causal conclusions. Further longitudinal, well-phenotyped, mechanistically informed studies are needed to determine whether microbiome-related pathways have measurable clinical relevance in human VTE.

NutrientsVol. 18(8)
Medical University of Silesia (PL)
Openalex Percentile: Top 25%
Gut microbiota and health
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Venous Thromboembolism and Gut Dysbiosis: Mechanistic Links Between Endotoxemia, Microbial Metabolites, and Thromboinflammation — Agata Stanek, Leon Smółka, et al. · Nutrients (2026) | TGRS Research Map | TGRS