Bimodal Fluorescent Conjugate Based on Prostate-Specific Membrane Antigen Ligands with the Chelating Agent DOTA and SulfoCy5 Dye: Synthesis, Radiolabeling, and Biological Activity
for PSMA was confirmed in a murine LNCaP xenograft model: its effective accumulation in tumors and kidneys, as well as relatively rapid elimination from non-target tissues, make it a promising agent for PET imaging but not radionuclide therapy.
Authors
- А. А. Ларенков (ORCID: https://orcid.org/0000-0003-4810-4346)
- Stanislav A. Petrov (ORCID: https://orcid.org/0000-0002-6000-6100)
- Elena Kimovna Beloglazkina (ORCID: https://orcid.org/0000-0001-6796-8241)
- Radik R. Shafikov (ORCID: https://orcid.org/0000-0002-9349-5211)
- Aleksei E. Machulkin (ORCID: https://orcid.org/0000-0001-7975-0346)
- Kristina A. Petrosova
- Dmitry A. Skvortsov (ORCID: https://orcid.org/0000-0001-8300-459X)
- A. S. Lunev (ORCID: https://orcid.org/0000-0002-8392-8343)
- Yu. A. Mitrofanov
- Mariia N. Ivashkovaskaia (ORCID: https://orcid.org/0009-0008-6026-0329)
- Nina S. Butakova
Institutions
- Peoples' Friendship University of Russia (RU)
- Lomonosov Moscow State University (RU)
- Institute of Bioorganic Chemistry (RU)
- State Scientific Center of the Russian Federation - Federal Medical Biophysical Center named after A.I. Burnazyan (RU)
Publication Details
- Journal
- International Journal of Molecular Sciences
- Published
- 2026-04-14
- DOI
- https://doi.org/10.3390/ijms27083502
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Russian Science Foundation
- Lomonosov Moscow State University