Drug-coated balloon angioplasty for symptomatic vertebral artery origin stenosis: a real-world analysis of efficacy and predictors for bailout stenting

Objective: This study aims to evaluate the preliminary efficacy and safety of drug-coated balloon (DCB) angioplasty for treating symptomatic vertebral artery origin stenosis (VAOS) in a real-world setting and to investigate potential factors necessitating intraoperative bailout stenting (BS). Methods: -index) and the Hosmer-Lemeshow goodness-of-fit test. Results: = 0.9158). Conclusion: DCB angioplasty was associated with favorable angiographic durability in symptomatic VAOS, with similar long-term patency between balloon-only and bailout stent strategies. Higher diastolic blood pressure, and concomitant carotid stenosis were associated with bailout stenting.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-04-14
DOI
https://doi.org/10.3389/fneur.2026.1804766
Primary Topic
Cerebrovascular and Carotid Artery Diseases
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article
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article

Drug-coated balloon angioplasty for symptomatic vertebral artery origin stenosis: a real-world analysis of efficacy and predictors for bailout stenting

Dong Zhang, Yuerong Dong, Yan Zhang, Qing He
Frontiers in Neurology
Cerebrovascular and Carotid Artery Diseases
article

Drug-coated balloon angioplasty for symptomatic vertebral artery origin stenosis: a real-world analysis of efficacy and predictors for bailout stenting

Dong Zhang, Yuerong Dong, Yan Zhang, Qing He
article en

Abstract

Objective: This study aims to evaluate the preliminary efficacy and safety of drug-coated balloon (DCB) angioplasty for treating symptomatic vertebral artery origin stenosis (VAOS) in a real-world setting and to investigate potential factors necessitating intraoperative bailout stenting (BS). Methods: -index) and the Hosmer-Lemeshow goodness-of-fit test. Results: = 0.9158). Conclusion: DCB angioplasty was associated with favorable angiographic durability in symptomatic VAOS, with similar long-term patency between balloon-only and bailout stent strategies. Higher diastolic blood pressure, and concomitant carotid stenosis were associated with bailout stenting.

Frontiers in NeurologyVol. 17
Xuzhou Medical College (CN), Affiliated Hospital of Xuzhou Medical College (CN)
Good health and well-being
Openalex Percentile: Top 26%
Cerebrovascular and Carotid Artery Diseases
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Drug-coated balloon angioplasty for symptomatic vertebral artery origin stenosis: a real-world analysis of efficacy and predictors for bailout stenting — Dong Zhang, Yuerong Dong, et al. · Frontiers in Neurology (2026) | TGRS Research Map | TGRS