Vaccine adherence among adult cancer survivors in the United States

Adults with cancer are at risk for complications from vaccine-preventable diseases, yet vaccine adherence in this population remains poorly characterized. This cross-sectional study used the National Health Interview Survey 2019 to 2023 to examine trends in influenza, pneumococcal, and shingles vaccines among adults aged ≥50 years with cancer. Of the 6,533 respondents included, only 30.6% (95% confidence interval [CI; 29.3%, 31.9%]) reported receiving all three recommended vaccines. Factors associated with lower vaccination adherence included younger age (odds ratio [OR] comparing ages ≥75 to 50 to 64 years 5.39; 95% CI [4.70, 6.18]), male sex (OR 0.81; 95% CI [0.73, 0.90]), Black (OR 0.59; 95% CI [0.47, 0.73]) or Hispanic race/ethnicity (OR 0.69; 95% CI [0.52, 0.92]), Medicaid insurance (OR 0.79; 95% CI [0.65, 0.96]), and lower educational attainment (OR 0.65; 95% CI [0.58, 0.73]). Preventable disease vaccination remains subpar in the adult cancer population, and further efforts including targeted interventions are necessary to improve preventative health efforts in these patients.

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Publication Details

Journal
JNCI Journal of the National Cancer Institute
Published
2026-04-10
DOI
https://doi.org/10.1093/jnci/djag118
Primary Topic
Influenza Virus Research Studies
Type
article
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article

Vaccine adherence among adult cancer survivors in the United States

Kenneth J. Mukamal, Kimberly Feng, Cancan Zhang
JNCI Journal of the National Cancer Institute
Influenza Virus Research Studies
article

Vaccine adherence among adult cancer survivors in the United States

Kenneth J. Mukamal, Kimberly Feng, Cancan Zhang
article en

Abstract

Adults with cancer are at risk for complications from vaccine-preventable diseases, yet vaccine adherence in this population remains poorly characterized. This cross-sectional study used the National Health Interview Survey 2019 to 2023 to examine trends in influenza, pneumococcal, and shingles vaccines among adults aged ≥50 years with cancer. Of the 6,533 respondents included, only 30.6% (95% confidence interval [CI; 29.3%, 31.9%]) reported receiving all three recommended vaccines. Factors associated with lower vaccination adherence included younger age (odds ratio [OR] comparing ages ≥75 to 50 to 64 years 5.39; 95% CI [4.70, 6.18]), male sex (OR 0.81; 95% CI [0.73, 0.90]), Black (OR 0.59; 95% CI [0.47, 0.73]) or Hispanic race/ethnicity (OR 0.69; 95% CI [0.52, 0.92]), Medicaid insurance (OR 0.79; 95% CI [0.65, 0.96]), and lower educational attainment (OR 0.65; 95% CI [0.58, 0.73]). Preventable disease vaccination remains subpar in the adult cancer population, and further efforts including targeted interventions are necessary to improve preventative health efforts in these patients.

JNCI Journal of the National Cancer Institute
Beth Israel Deaconess Medical Center (US)
Good health and well-being
Openalex Percentile: Top 6%
Influenza Virus Research Studies
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