Design and Evaluation of Gellan/Boron-dipyrromethene as a Photoactive Hydrogel and Efficiency as Antiyeast Activity
sp. strain KG2 showed a 90 % reduction in colony-forming units within 24 h, supported by fluorescence imaging. Its hydrophilic sugar-rich network enhances cellular uptake, leading to notable light-induced cytotoxicity in RAW 264.7 macrophages. Molecular docking with concanavalin A, a model lectin, showed good protein-ligand interactions that may enhance yeast inhibition. GN@BODIPY acts as a multifunctional platform, a fluorescent gel, a photoinitiator/catalyst, and a potential antifungal and photodynamic therapy agent.
Authors
- Jhuma Ganguly (ORCID: https://orcid.org/0000-0001-5119-6144)
- Avishek Banik (ORCID: https://orcid.org/0000-0001-5029-2708)
- Ayon Jyoti Karmakar (ORCID: https://orcid.org/0000-0002-8409-503X)
- Shubhankar Ghorai (ORCID: https://orcid.org/0000-0003-1980-9574)
- D. C. BERA
- Prasanta Kumar Datta (ORCID: https://orcid.org/0000-0001-9476-7656)
- Pijus Ghorai (ORCID: https://orcid.org/0009-0000-5175-621X)
- Sanu Pramanick
- Sharmila Das
- Debkanta Ghosh (ORCID: https://orcid.org/0009-0006-1057-8641)
Institutions
- Indian Institute of Technology Kharagpur (IN)
- Presidency University (IN)
- Presidency University (BD)
- Institute of Engineering Science (RU)
- Interaction Design (United Kingdom) (GB)
Publication Details
- Journal
- ACS Applied Bio Materials
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1021/acsabm.6c00177
- Primary Topic
- Hydrogels: synthesis, properties, applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00