Phoenix Sepsis Score

The Phoenix sepsis score defines sepsis for children born full term (37 weeks gestational age or greater) who are hospitalized using lab and vital sign criteria based on the presence of end-organ dysfunction. Septic shock is defined as the presence of cardiovascular dysfunction in the context of sepsis. The Phoenix score is calculated by adding the highest subscores within a 24-hour period (the first 24 hours of hospitalization). In both derivation and validation testing, the Phoenix criteria outperformed the International Pediatric Sepsis Consensus Conference (IPSCC) criteria. The Phoenix criteria may be more physiologically accurate than SIRS given that many children may meet SIRS criteria (e.g. fever and tachycardia) without truly having sepsis due to viral infections, for example.

Authors

Publication Details

Journal
Evidence to Action Official Journal of MDCalc
Published
2026-04-14
DOI
https://doi.org/10.65357/001c.158895
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Phoenix Sepsis Score

Derek Tam
Evidence to Action Official Journal of MDCalc
Neonatal and Maternal Infections
article

Phoenix Sepsis Score

Derek Tam
article en

Abstract

The Phoenix sepsis score defines sepsis for children born full term (37 weeks gestational age or greater) who are hospitalized using lab and vital sign criteria based on the presence of end-organ dysfunction. Septic shock is defined as the presence of cardiovascular dysfunction in the context of sepsis. The Phoenix score is calculated by adding the highest subscores within a 24-hour period (the first 24 hours of hospitalization). In both derivation and validation testing, the Phoenix criteria outperformed the International Pediatric Sepsis Consensus Conference (IPSCC) criteria. The Phoenix criteria may be more physiologically accurate than SIRS given that many children may meet SIRS criteria (e.g. fever and tachycardia) without truly having sepsis due to viral infections, for example.

Evidence to Action Official Journal of MDCalcVol. 012026(01)
Good health and well-being
Openalex Percentile: Top 11%
Neonatal and Maternal Infections
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