Epigenetic regulation by gut microbiota-derived metabolites in celiac disease
) in restoring epithelial homeostasis and reprogramming detrimental miRNA profiles. Therefore, the microbiota-metabolite-epigenetic interplay emerges as a pivotal bridge between genetic risk and clinical disease, offering novel preventive and adjunctive therapeutic targets beyond strict gluten avoidance.
Authors
- Roghayeh Faraji Akhijahani
- Shahram Abdoli Oskouei
- Masoud Lahouty (ORCID: https://orcid.org/0000-0003-2302-2192)
- Marzieh Khaneshi
- Baharak Maddahi (ORCID: https://orcid.org/0000-0002-6067-8011)
- Fatemeh Alizadeh
- Amirhossein Faghih Ojaroodi
- Armin Ghahremanzadeh
Institutions
- Tabriz University of Medical Sciences (IR)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1016/j.bbrep.2026.102584
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Student Research Committee, Tabriz University of Medical Sciences