Real-time characterisation of microbe-induced inflammation using a novel zebrafish larval corneal injury and infection model
). Infection with live bacteria induced robust, sustained neutrophil and macrophage recruitment, marked by increased neutrophil speed and migratory distance. This model enables dynamic in vivo visualization of immune cell dynamics, offering a powerful and scalable platform to accelerate the discovery and screening of novel immunomodulators for MK.
Authors
- Adriano G. Rossi (ORCID: https://orcid.org/0000-0003-3173-9521)
- Bethany Mills (ORCID: https://orcid.org/0000-0003-3209-9490)
- Kelvin Cheng (ORCID: https://orcid.org/0000-0001-5618-082X)
- Carl S. Tucker
- Fraser Laidlaw
- Stephen Mitchell
- Justyna Cholewa-Waclaw
Institutions
- Centre for Inflammation Research (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Communications Biology
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1038/s42003-026-09985-1
- Primary Topic
- Zebrafish Biomedical Research Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00