Sharing a whole-/total-body [<sup>18</sup>F]FDG-PET/CT dataset with CT-derived segmentations: an ENHANCE.PET initiative.
F]fluoro-D-glucose (FDG)-Positron Emission Tomography/Computed Tomography (PET/CT) studies, consisting of 1,683 PET/CT images and the corresponding CT-derived segmentations of 130 target regions. This multi-center dataset includes images from individuals without overt disease and patients with a range of malignant and inflammatory pathologies, including arthritis, lymphoma, and melanoma, as well as cancers of the lung, head-neck, and genito-urinary tract. Target regions were first automatically segmented from CT images using an in-house software and subsequently verified and corrected by physicians-in-training. In total, the segmented regions encompass 130 volumes, including abdominal organs, muscles, bones, cardiac subregions, vessels, adipose tissue, and skeletal muscle around the third lumbar vertebra. PET/CT images and corresponding CT-derived segmentations are provided in anonymized NIfTI format. The dataset can be used for deep learning training, validation, or multi-modality image analysis and thus fills an important gap in available resources to advance the use of PET/CT data in clinical management.
Authors
- M Chen
- Elisabetta Abenavoli
- Josef Yu (ORCID: https://orcid.org/0000-0003-1426-1538)
- Barbara Katharina Geist (ORCID: https://orcid.org/0000-0003-0098-0048)
- H Wirtz
- Osama Raslan (ORCID: https://orcid.org/0000-0003-4056-3169)
- Lalith Kumar Shiyam Sundar (ORCID: https://orcid.org/0000-0003-3004-7937)
- Sebastian Gutschmayer (ORCID: https://orcid.org/0000-0002-7908-845X)
- Abhijit J. Chaudhari (ORCID: https://orcid.org/0000-0002-4211-1900)
- Pia Linder (ORCID: https://orcid.org/0000-0002-3517-6335)
- Ivo Rausch (ORCID: https://orcid.org/0000-0002-4007-1669)
- Johanna Pappisch
- Stefan Gruenert
- Armin Frille (ORCID: https://orcid.org/0000-0003-2843-3863)
- Daria Ferrara (ORCID: https://orcid.org/0000-0002-8711-8081)
- Teresa Kerkhoff
- Swen Hesse (ORCID: https://orcid.org/0000-0002-2055-2764)
- Fabian Schmidt (ORCID: https://orcid.org/0000-0003-1886-4803)
- Smilla Pusitz
- Benjamin A. Spencer
- Manuel Pires
- M H Hacker
- Guobao Wang
- Thomas Beyer
- O Sabri
- Ramsey D. Badawi
- Roberto Sciagra
- Siba P Raychaudhuri
- Simon R Cherry
- Yasser G Abdelhafez
Institutions
- Siemens (Germany) (DE)
- King's College London (GB)
- LMU Klinikum (DE)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- University Hospital Leipzig (DE)
- University of California Davis Medical Center (US)
- Medical University of Vienna (AT)
- University of Tübingen (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of California, Davis (US)
- Leipzig University (DE)
Publication Details
- Journal
- PubMed
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1038/s41597-026-07218-y
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00