A stimuli-responsive porous carbon nanovehicle for light-initiating and thermo-driving phototheranostics of renal cell carcinoma

fluorescent imaging of tumor sites. As a proof of concept, two nanovehicles, ICG@NCZIF and MB@NCZIF, are separately prepared and systematically compared. The better-performed ICG@NCZIF is further used in in vivo phototheranostics of renal cell carcinoma (RCC) and exhibits satisfactory results of tumor inhibition and accurate tumor imaging. Thus, the as-designed phototheranostics nanovehicle ICG@NCZIF holds potential for (pre)clinical translational development.

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Publication Details

Journal
iScience
Published
2026-04-14
DOI
https://doi.org/10.1016/j.isci.2026.115701
Primary Topic
Nanoplatforms for cancer theranostics
Type
article
Field-Weighted Citation Impact
0.00

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article

A stimuli-responsive porous carbon nanovehicle for light-initiating and thermo-driving phototheranostics of renal cell carcinoma

Shiquan Xu, Mengzhen Lv, Cheng Qiu, Zhaojie Su et al.
iScience
Nanoplatforms for cancer theranostics
article

A stimuli-responsive porous carbon nanovehicle for light-initiating and thermo-driving phototheranostics of renal cell carcinoma

Shiquan Xu, Mengzhen Lv, Cheng Qiu, Zhaojie Su, Jianfei Xia, Runhe Zhou, Xiyue Cao
article en

Abstract

fluorescent imaging of tumor sites. As a proof of concept, two nanovehicles, ICG@NCZIF and MB@NCZIF, are separately prepared and systematically compared. The better-performed ICG@NCZIF is further used in in vivo phototheranostics of renal cell carcinoma (RCC) and exhibits satisfactory results of tumor inhibition and accurate tumor imaging. Thus, the as-designed phototheranostics nanovehicle ICG@NCZIF holds potential for (pre)clinical translational development.

iScienceVol. 29(5)
Qingdao University (CN), Xiamen University (CN), First Affiliated Hospital of Xiamen University (CN), Qilu Hospital of Shandong University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 31%
Nanoplatforms for cancer theranostics
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