A stimuli-responsive porous carbon nanovehicle for light-initiating and thermo-driving phototheranostics of renal cell carcinoma
fluorescent imaging of tumor sites. As a proof of concept, two nanovehicles, ICG@NCZIF and MB@NCZIF, are separately prepared and systematically compared. The better-performed ICG@NCZIF is further used in in vivo phototheranostics of renal cell carcinoma (RCC) and exhibits satisfactory results of tumor inhibition and accurate tumor imaging. Thus, the as-designed phototheranostics nanovehicle ICG@NCZIF holds potential for (pre)clinical translational development.
Authors
- Shiquan Xu
- Mengzhen Lv
- Cheng Qiu (ORCID: https://orcid.org/0000-0002-6482-7619)
- Zhaojie Su
- Jianfei Xia
- Runhe Zhou
- Xiyue Cao
Institutions
- Qingdao University (CN)
- Xiamen University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- iScience
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1016/j.isci.2026.115701
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China