Dynamic optic nerve sheath diameter monitoring for intracranial pressure assessment in TBI patients

Objective: To explore the role of dynamic monitoring of optic nerve sheath diameter (ONSD) in the assessment of intracranial pressure (ICP) in patients with traumatic brain injury (TBI). Methods: A prospective study was conducted on patients with traumatic brain injury admitted to the Neurocritical Care Unit of the First People's Hospital of Changde between 01/06/2024 and 30/09/2025. All enrolled patients underwent invasive ICP monitoring. A 14-5 MHz ultrasound probe was used to measure the ONSD in both eyes, with ICP values recorded simultaneously during ONSD measurements. Data were collected both before and 20 min after mannitol infusion administration. The Wilcoxon signed-rank test was used to compare ONSD and ICP before and after mannitol infusion, and Spearman correlation analysis was performed to assess their relationship. Results: < 0.01). Conclusion: Dynamic monitoring of ONSD can reflect changes in intracranial pressure in patients with TBI, demonstrating potential utility in the assessment of intracranial hypertension.