Incidentally Detected Low-Grade Appendiceal Mucinous Neoplasm Following Laparoscopic Appendectomy for Acute Appendicitis

Appendiceal mucinous neoplasms are rare entities that account for a small proportion of all gastrointestinal malignancies and are most often discovered incidentally on histopathological examination of appendectomy specimens. We present the case of a 36-year-old woman who presented to the emergency department with acute right lower quadrant abdominal pain and was found to have acute appendicitis on computed tomography imaging. She underwent an uncomplicated laparoscopic appendectomy, and final pathology revealed a low-grade appendiceal mucinous neoplasm (LAMN) confined to the appendix, staged as pTis(LAMN). Postoperative colonoscopy was performed to evaluate the appendiceal orifice and exclude synchronous colorectal lesions. This case highlights the importance of routine histopathological examination of all appendectomy specimens and the need for appropriate postoperative surveillance in patients with incidentally discovered appendiceal mucinous neoplasms.

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Publication Details

Journal
Cureus
Published
2026-04-14
DOI
https://doi.org/10.7759/cureus.107008
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Incidentally Detected Low-Grade Appendiceal Mucinous Neoplasm Following Laparoscopic Appendectomy for Acute Appendicitis

Jay Oberoi, Oscar A Vazquez, Felipe Alberto Camacho Cordovez, Mridul Pansari et al.
Cureus
Intraperitoneal and Appendiceal Malignancies
article

Incidentally Detected Low-Grade Appendiceal Mucinous Neoplasm Following Laparoscopic Appendectomy for Acute Appendicitis

Jay Oberoi, Oscar A Vazquez, Felipe Alberto Camacho Cordovez, Mridul Pansari, Anupam Gupta
article en

Abstract

Appendiceal mucinous neoplasms are rare entities that account for a small proportion of all gastrointestinal malignancies and are most often discovered incidentally on histopathological examination of appendectomy specimens. We present the case of a 36-year-old woman who presented to the emergency department with acute right lower quadrant abdominal pain and was found to have acute appendicitis on computed tomography imaging. She underwent an uncomplicated laparoscopic appendectomy, and final pathology revealed a low-grade appendiceal mucinous neoplasm (LAMN) confined to the appendix, staged as pTis(LAMN). Postoperative colonoscopy was performed to evaluate the appendiceal orifice and exclude synchronous colorectal lesions. This case highlights the importance of routine histopathological examination of all appendectomy specimens and the need for appropriate postoperative surveillance in patients with incidentally discovered appendiceal mucinous neoplasms.

Cureus
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Intraperitoneal and Appendiceal Malignancies
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