Differential Hematotoxic Activity of Southeast Asian Pit Viper Venoms: The Cross-Neutralizing Effect of Available Antivenoms
These findings highlight the limited cross-neutralization capacity of monovalent antivenoms against arboreal pit viper hematotoxicity. In contrast, HPAV demonstrated broad cross-neutralizing activity and may represent a practical therapeutic option for Southeast Asian pit viper envenoming when species-specific antivenoms are unavailable.
Authors
- Muhamad Rusdi Ahmad Rusmili (ORCID: https://orcid.org/0000-0002-0327-060X)
- Janeyuth Chaisakul (ORCID: https://orcid.org/0000-0002-2367-8792)
- Dollapak Apipongrat (ORCID: https://orcid.org/0000-0002-6654-6431)
- Wittawat Chantkran (ORCID: https://orcid.org/0000-0001-7877-0222)
- Khatsophon Poonaya
- Kornkanok Thapanasopon
Institutions
- International Islamic University Malaysia (MY)
- Phramongkutklao Hospital (TH)
- Phramongkutklao College of Medicine
Publication Details
- Journal
- Medical Sciences
- Published
- 2026-04-14
- DOI
- https://doi.org/10.3390/medsci14020199
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ananda Mahidol Foundation
- U.S. Army Medical Department