A cut-off value for endothelial dysfunction based on the triglyceride-glucose index

We defined triglyceride-glucose (TyG) index < 8.52 as a low TyG index and TyG index ≥ 8.52 as a high TyG index, and divided the subjects into nine groups based on the levels of TyG index and fasting blood glucose (FBG) levels: FBG levels < 90 mg/dL and low TyG index, FBG levels < 90 mg/dL and high TyG index, FBG levels of 90-94 mg/dL and low TyG index, FBG levels of 90-94 mg/dL and high TyG index, FBG levels of 95-99 mg/dL and low TyG index, FBG levels of 95-99 mg/dL and high TyG index, FBG levels of 100-125 mg/dL and low TyG index, FBG levels of 100-125 mg/dL and high TyG index, and diabetes mellitus. The odds ratios for endothelial dysfunction were significantly higher in groups with high TyG index and any levels of FBG, and the group with low TyG index and FBG levels of 95-99 mg/dL, the group with low TyG index and FBG levels of 100-125 mg/dL and the diabetes mellitus group than the FBG levels < 90 mg/dL and low TyG index group. Even at a low TyG index, subjects with FBG levels ≥ 95 mg/dL might have a higher risk for endothelial dysfunction.