Association of Underweight, Sarcopenia, and Cancer Cachexia with Survival Outcomes in Hypopharyngeal Cancer Radiotherapy

Pretreatment underweight and cancer cachexia negatively impact survival outcomes, including locoregional control, in HPC radiotherapy. Prospective studies with standardized nutritional assessment protocols, pre-specified intervention arms, and sufficient sample sizes are essential to validate these findings and to establish the clinical benefit of pre-treatment nutritional optimization in this patient population.

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Publication Details

Journal
Cancers
Published
2026-04-14
DOI
https://doi.org/10.3390/cancers18081244
Primary Topic
Nutrition and Health in Aging
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of Underweight, Sarcopenia, and Cancer Cachexia with Survival Outcomes in Hypopharyngeal Cancer Radiotherapy

Akira Torii, Koji Tsukamoto, Sho Iwaki, Taiki Takaoka et al.
Cancers
Nutrition and Health in Aging
article

Association of Underweight, Sarcopenia, and Cancer Cachexia with Survival Outcomes in Hypopharyngeal Cancer Radiotherapy

Akira Torii, Koji Tsukamoto, Sho Iwaki, Taiki Takaoka, Shinichi Iwasaki, Dai Okazaki, Natsuo Tomita, Takuma Matoba, Masanosuke Oguri, Masanari Niwa, Kiyoshi Minohara, Nozomi Kita, Akio Hiwatashi, Daisuke Kawakita
article en

Abstract

Pretreatment underweight and cancer cachexia negatively impact survival outcomes, including locoregional control, in HPC radiotherapy. Prospective studies with standardized nutritional assessment protocols, pre-specified intervention arms, and sufficient sample sizes are essential to validate these findings and to establish the clinical benefit of pre-treatment nutritional optimization in this patient population.

CancersVol. 18(8)
Nagoya City University (JP)
Japan Society for the Promotion of Science
Good health and well-being
Openalex Percentile: Top 21%
Nutrition and Health in Aging
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Association of Underweight, Sarcopenia, and Cancer Cachexia with Survival Outcomes in Hypopharyngeal Cancer Radiotherapy — Akira Torii, Koji Tsukamoto, et al. · Cancers (2026) | TGRS Research Map | TGRS