Successful treatment of cutaneous small-vessel vasculitis with upadacitinib: a Case Report

Cutaneous small-vessel vasculitis (CSVV) is a rare skin vasculitis that mainly affects small blood vessels and is often caused by certain drugs or diseases. When the condition is severe, skin ulcers may occur, accompanied by severe pain, which can affect daily life. This article reports a case in which the patient had a poor response to conventional corticosteroid therapy, with the condition continuing to deteriorate. Following 3 months of combination therapy with oral upadacitinib, the skin lesions nearly healed completely. This provides a new perspective for the treatment of CSVV and offers clinicians an additional treatment option.