Chemical Modification of 2,6,9-Trisubstituted Purine CDK Inhibitors: <i>tert</i> -Butylation at <i>N</i> 7/ <i>N</i> 9 and Access to 2,6,7-Trisubstituted Analogs
-butyl)-2,6-dichloropurines-has been developed by a new method to enable targeted substitution at the chlorine-bearing positions.
Authors
- Jakub Stýskala (ORCID: https://orcid.org/0000-0003-1726-8604)
- Michał Valenta (ORCID: https://orcid.org/0000-0003-1694-3428)
Institutions
- Palacký University Olomouc (CZ)
Publication Details
- Journal
- ACS Omega
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1021/acsomega.5c10284
- Primary Topic
- Biochemical and Molecular Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Univerzita Palackého v Olomouci