Caregiver-Targeted Online Multicomponent Intervention and Quality of Life in Alzheimer’s Disease: A Randomized Controlled Trial

OBJECTIVES: To examine whether a brief, fully online caregiver-targeted multicomponent psychological intervention improves self-reported quality of life (QoL) in people with Alzheimer's disease (AD). METHODS: = 28). Caregivers in the intervention group completed an 8-week online program combining psychoeducation and mindfulness. Outcomes were assessed at baseline and post-intervention by blinded assessors. The primary outcome was QoL assessed with the QoL-AD. Group-by-time effects were analyzed using linear mixed-effects models. RESULTS: = .039). No significant effects were observed for cognitive performance. CONCLUSIONS: A brief caregiver-targeted online intervention was associated with improved QoL and stabilization of neuropsychiatric symptoms in people with AD. CLINICAL IMPLICATIONS: Trial registration: ClinicalTrials.gov, NCT04280861 (registered 17 February 2020).