Association of Serum ADA Levels in Pulmonary Tuberculosis: A Systematic Review and Meta-Analysis

Serum ADA levels were significantly elevated in patients with PTB, indicating a consistent biological association with disease status. However, given the high heterogeneity and the absence of diagnostic accuracy measures (e.g., sensitivity and specificity), these findings should not be interpreted as evidence of clinical diagnostic performance. Further diagnostic test accuracy studies are required to establish its clinical utility.

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Publication Details

Journal
International Journal of Environmental Research and Public Health
Published
2026-04-14
DOI
https://doi.org/10.3390/ijerph23040498
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Serum ADA Levels in Pulmonary Tuberculosis: A Systematic Review and Meta-Analysis

Jongkonnee Thanasai, Jirarat Songsri, Wiyada Kwanhian Klangbud, Anchalee Chittamma et al.
International Journal of Environmental Research and Public Health
Tuberculosis Research and Epidemiology
article

Association of Serum ADA Levels in Pulmonary Tuberculosis: A Systematic Review and Meta-Analysis

Jongkonnee Thanasai, Jirarat Songsri, Wiyada Kwanhian Klangbud, Anchalee Chittamma, Jitbanjong Tangpong
article en

Abstract

Serum ADA levels were significantly elevated in patients with PTB, indicating a consistent biological association with disease status. However, given the high heterogeneity and the absence of diagnostic accuracy measures (e.g., sensitivity and specificity), these findings should not be interpreted as evidence of clinical diagnostic performance. Further diagnostic test accuracy studies are required to establish its clinical utility.

International Journal of Environmental Research and Public HealthVol. 23(4)
Nakhon Phanom University (TH), Mahasarakham University (TH), Mahidol University (TH), Ramathibodi Hospital (TH), Walailak University (TH)
Good health and well-being
Openalex Percentile: Top 23%
Tuberculosis Research and Epidemiology
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