Diagnosis-to-Treatment Interval Is Associated With Outcomes in Follicular Lymphoma Treated with Immunochemotherapy
Short diagnosis-to-treatment interval independently predicts inferior outcomes in follicular lymphoma. Using international discovery and validation cohorts, we demonstrate its prognostic value beyond established prognostic indices, with implications for risk stratification, clinical trial design, and interpretation.
Authors
- Eliza A. Hawkes (ORCID: https://orcid.org/0000-0002-0376-2559)
- Michael Roost Clausen (ORCID: https://orcid.org/0000-0003-3218-3633)
- Richard Burack (ORCID: https://orcid.org/0000-0002-5584-584X)
- Jonathon Brett Cohen (ORCID: https://orcid.org/0000-0002-2723-6481)
- Vít Procházka (ORCID: https://orcid.org/0000-0002-9861-3117)
- Lasse Hjort Jakobsen (ORCID: https://orcid.org/0000-0001-6575-7686)
- Maher K. Gandhi
- Andrea Janíková (ORCID: https://orcid.org/0000-0002-2647-7769)
- Prokop Vodička (ORCID: https://orcid.org/0000-0002-7848-1268)
- Peter de Nully Brown (ORCID: https://orcid.org/0000-0002-6522-4086)
- Jonathan W. Friedberg (ORCID: https://orcid.org/0000-0002-1420-5563)
- Izidore S. Lossos (ORCID: https://orcid.org/0000-0002-9346-9013)
- Dai Chihara (ORCID: https://orcid.org/0000-0002-1153-2294)
- Eric Mou (ORCID: https://orcid.org/0000-0002-9865-4517)
- Carla Casulo (ORCID: https://orcid.org/0000-0003-4998-9932)
- Brad S. Kahl (ORCID: https://orcid.org/0000-0003-0459-6609)
- Chan Yoon Cheah (ORCID: https://orcid.org/0000-0001-7988-1565)
- Björn E. Wahlin (ORCID: https://orcid.org/0000-0003-3566-8847)
- James R. Cerhan (ORCID: https://orcid.org/0000-0002-7482-178X)
- Christopher R. Flowers (ORCID: https://orcid.org/0000-0002-9524-3990)
- Caroline E. Dietrich (ORCID: https://orcid.org/0000-0001-8231-8183)
- Marek Trněný (ORCID: https://orcid.org/0000-0002-6952-6073)
- Y Wang
- Diego Villa
- Peter Martin
- Robert Kridel (ORCID: https://orcid.org/0000-0003-0287-7124)
- David Belada
- Hervé Ghesquieres
- Melissa C Larson
- Elliot J Cahn
- Tarec C El-Galaly
- Karin E Smedby
- Heidi Mocikova
- Thomas M Habermann
- Laurie H Sehn
- Matthew J Maurer (ORCID: https://orcid.org/0000-0002-1867-0526)
Institutions
- Université Claude Bernard Lyon 1 (FR)
- University of Iowa (US)
- BC Cancer Agency (CA)
- Mayo Clinic (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Miami (US)
- Emory University (US)
- Washington University in St. Louis (US)
- Charles University (CZ)
- Aalborg University Hospital (DK)
- Sir Charles Gairdner Hospital (AU)
- Aarhus University Hospital (DK)
- WinnMed (US)
- Princess Margaret Cancer Centre (CA)
- Rigshospitalet (DK)
- Karolinska Institutet (SE)
- University of Rochester Medical Center (US)
- NYU Langone Health (US)
- Vejle Sygehus (DK)
- University Hospital Brno (CZ)
- University Hospital Olomouc (CZ)
- Hôpital Lyon Sud (FR)
- University Hospital Hradec Králové (CZ)
- University Hospital Kralovske Vinohrady (CZ)
- Olivia Newton-John Cancer Wellness & Research Centre (AU)
- Austin Health (AU)
- University of Rochester (US)
Publication Details
- Journal
- Blood
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1182/blood.2026033090
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00