Donor selection for patients with HLA-homozygous haplotypes in allogeneic hematopoietic stem cell transplantation
HIGHLIGHTS: Registry analysis of first allogeneic transplant in HLA-homozygous recipients.Overall survival did not significantly differ with related donor hetero-to-homo or cord blood hetero-to-homo transplantation.Cord blood homo-to-homo transplantation was associated with inferior survival in the primary analysis.
Authors
- Yuta Hasegawa (ORCID: https://orcid.org/0000-0002-9925-2093)
- Noboru Asada (ORCID: https://orcid.org/0000-0001-7322-5460)
- Kazunori Imada (ORCID: https://orcid.org/0000-0002-0945-0513)
- Makoto Iwasaki (ORCID: https://orcid.org/0000-0002-7564-157X)
- Masahiro Hirayama (ORCID: https://orcid.org/0000-0002-6850-2782)
- Minoru Kanaya (ORCID: https://orcid.org/0000-0002-0035-8657)
- Noriyoshi Yoshinaga (ORCID: https://orcid.org/0009-0002-6508-9432)
- Makoto Onizuka
- Mineo Kurokawa
- Yukio Kondo
- Yoshinobu Kanda
- Noriko Doki
- Satoko Morishima
- Naoyuki Uchida
- Fumihiko Kimura
- Junya Kanda
- Koji Kato
- Tatsuo Ichinohe
- Masatsugu Tanaka
- Shinichi Kako
- Keisuke Kataoka
- Takahiro Fukuda
- Tetsuya Nishida
- Toshiro Kawakita
- Yoshiko Atsuta
Institutions
- Hiroshima University (JP)
- Tokai University (JP)
- Kyushu University (JP)
- Jichi Medical University (JP)
- Aichi Medical University (JP)
- Mie University (JP)
- Keio University (JP)
- Kyoto University (JP)
- Kanagawa Prefectural Hospital Organization (JP)
- Tokyo Metropolitan Komagome Hospital (JP)
- Toyama Prefectural Central Hospital (JP)
- Okayama University Hospital (JP)
- University of Tokyo Hospital (JP)
- Osaka Hospital (JP)
- Japanese Red Cross Nagoya Daiichi Hospital (JP)
- Hokkaido University Hospital (JP)
- The Japanese Data Center for Hematopoietic Cell Transplantation (JP)
- Kumamoto Medical Center (JP)
- Jichi Medical University Saitama Medical Center (JP)
- Toranomon Hospital (JP)
- Kanagawa Cancer Center
- National Defense Medical College (JP)
Publication Details
- Journal
- Annals of Hematology
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1007/s00277-026-06994-2
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science