Transapical TAVR in Native Aortic Regurgitation With Chronic Type A Dissection

BACKGROUND: Severe native aortic regurgitation complicated by chronic Stanford type A dissection represents an extreme-risk scenario in which surgery may be prohibitive and transfemoral transcatheter aortic valve replacement may increase procedural risk. CASE PRESENTATION: An elderly frail patient with symptomatic severe native aortic regurgitation and localized chronic ascending aortic dissection was deemed unsuitable for surgery. Preprocedural computed tomography demonstrated a short dissection segment above the annulus without sinus or coronary involvement and without imaging features of instability. HOW WE DID IT: To minimize mechanical stress on the dissected ascending aorta, a transapical approach was selected to avoid arch manipulation and enable straight-line coaxial valve delivery. A leaflet-anchoring valve was implanted under fluoroscopic and transesophageal echocardiographic guidance with rapid pacing to ensure controlled deployment. OUTCOME: The procedure was completed without dissection progression or significant paravalvular regurgitation. Follow-up imaging confirmed durable valve function and stable dissection morphology. TAKE-HOME MESSAGE: In carefully selected nonsurgical patients with severe native AR and localized chronic type A dissection, transapical TAVR may represent a mechanism-based rescue strategy by avoiding arch manipulation and enabling controlled valve deployment.

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Publication Details

Journal
JACC Case Reports
Published
2026-04-01
DOI
https://doi.org/10.1016/j.jaccas.2026.107820
Primary Topic
Aortic Disease and Treatment Approaches
Type
article
Field-Weighted Citation Impact
0.00

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article

Transapical TAVR in Native Aortic Regurgitation With Chronic Type A Dissection

W J Liu, Yanchao Li, Dacheng Li, Kai Zhang et al.
JACC Case Reports
Aortic Disease and Treatment Approaches
article

Transapical TAVR in Native Aortic Regurgitation With Chronic Type A Dissection

W J Liu, Yanchao Li, Dacheng Li, Kai Zhang, Meiling Xu
article en

Abstract

BACKGROUND: Severe native aortic regurgitation complicated by chronic Stanford type A dissection represents an extreme-risk scenario in which surgery may be prohibitive and transfemoral transcatheter aortic valve replacement may increase procedural risk. CASE PRESENTATION: An elderly frail patient with symptomatic severe native aortic regurgitation and localized chronic ascending aortic dissection was deemed unsuitable for surgery. Preprocedural computed tomography demonstrated a short dissection segment above the annulus without sinus or coronary involvement and without imaging features of instability. HOW WE DID IT: To minimize mechanical stress on the dissected ascending aorta, a transapical approach was selected to avoid arch manipulation and enable straight-line coaxial valve delivery. A leaflet-anchoring valve was implanted under fluoroscopic and transesophageal echocardiographic guidance with rapid pacing to ensure controlled deployment. OUTCOME: The procedure was completed without dissection progression or significant paravalvular regurgitation. Follow-up imaging confirmed durable valve function and stable dissection morphology. TAKE-HOME MESSAGE: In carefully selected nonsurgical patients with severe native AR and localized chronic type A dissection, transapical TAVR may represent a mechanism-based rescue strategy by avoiding arch manipulation and enabling controlled valve deployment.

JACC Case Reports
Qingdao University (CN), Affiliated Hospital of Qingdao University (CN)
National Major Science and Technology Projects of China
Openalex Percentile: Top 17%
Aortic Disease and Treatment Approaches
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Transapical TAVR in Native Aortic Regurgitation With Chronic Type A Dissection — W J Liu, Yanchao Li, et al. · JACC Case Reports (2026) | TGRS Research Map | TGRS