Dynamics of slow wave sleep in advanced Parkinson's disease: An entropy-based study
, Late-Early SampEn change was inversely related to dyskinesia severity (r = -0.75, pHolm = 0.068) and remained strong after adjustment for SWA (r = -0.90, pHolm = 0.018). These findings suggest that entropy-based measures capture dyskinesia-related alterations in nocturnal dynamics beyond SWA, providing a quantitative link between sleep neurophysiology and daytime motor complications in PD.
Authors
- Claudio Staedler
- Giovanni Lombardi
- Anna Castelnovo
- Ilaria Bertaina
- Salvatore Galati
- Alain Kaelin-Lang
- Luigi Fiorillo
Institutions
- University of Applied Sciences and Arts of Southern Switzerland (CH)
- Ente Ospedaliero Cantonale (CH)
- Università della Svizzera italiana (CH)
Publication Details
- Journal
- Neurobiology of Disease
- Published
- 2026-04-14
- DOI
- https://doi.org/10.1016/j.nbd.2026.107395
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Stiftung Synapsis - Alzheimer Forschung Schweiz AFS
- Parkinson Schweiz