Divergent Roles of SmHMGR2 and a Novel SmHMGR5 in Tanshinone Biosynthesis Revealed by CRISPR/Cas9-Mediated Knockout in Salvia miltiorrhiza

Authors

Yujun Zhao (ORCID: https://orcid.org/0000-0001-6687-6652)
Ziting Lan (ORCID: https://orcid.org/0000-0002-1275-5537)
Guanghong Cui
Chang‐Jiang‐Sheng Lai (ORCID: https://orcid.org/0000-0002-4581-2585)
Haiyan Zhang (ORCID: https://orcid.org/0000-0002-7279-7093)
Mei Tian
Tong Chen
Jianing Liu
Baolong Jin
Wenlong Shi (ORCID: https://orcid.org/0009-0003-6333-7137)
Qing Ma

Institutions

Dalian Institute of Chemical Physics (CN)
Dalian Medical University (CN)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
China Academy of Chinese Medical Sciences (CN)

Publication Details

Journal: International Journal of Molecular Sciences
Published: 2026-04-13
DOI: https://doi.org/10.3390/ijms27083485
Primary Topic: Plant biochemistry and biosynthesis
Type: article
Field-Weighted Citation Impact: 0.00

Funders

China Academy of Chinese Medical Sciences

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article

Divergent Roles of SmHMGR2 and a Novel SmHMGR5 in Tanshinone Biosynthesis Revealed by CRISPR/Cas9-Mediated Knockout in Salvia miltiorrhiza

Yujun Zhao, Ziting Lan, Guanghong Cui, Chang‐Jiang‐Sheng Lai et al.

Apr 13, 2026

International Journal of Molecular Sciences

Plant biochemistry and biosynthesis

article

Divergent Roles of SmHMGR2 and a Novel SmHMGR5 in Tanshinone Biosynthesis Revealed by CRISPR/Cas9-Mediated Knockout in Salvia miltiorrhiza

Yujun Zhao, Ziting Lan, Guanghong Cui, Chang‐Jiang‐Sheng Lai, Haiyan Zhang, Mei Tian, Tong Chen, Jianing Liu, Baolong Jin, Wenlong Shi, Qing Ma

April 13, 2026article en

Abstract

No abstract available for this paper.

International Journal of Molecular SciencesVol. 27(8)

Dalian Institute of Chemical Physics (CN), Dalian Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), China Academy of Chinese Medical Sciences (CN)

China Academy of Chinese Medical Sciences

Openalex Percentile: Top 26%

Plant biochemistry and biosynthesis

DOI Open Access PDF OpenAlex

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Divergent Roles of SmHMGR2 and a Novel SmHMGR5 in Tanshinone Biosynthesis Revealed by CRISPR/Cas9-Mediated Knockout in Salvia miltiorrhiza — Yujun Zhao, Ziting Lan, et al. · International Journal of Molecular Sciences (2026) | TGRS Research Map | TGRS