Dermoscopic Evaluation of Mild-to-Moderate Acne Vulgaris: A Correlation Analysis with Clinical Severity Scales

Background: Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit. Accurate and objective assessment of inflammatory activity remains a challenge in clinical practice. Dermoscopy, as a noninvasive imaging technique, enables visualization of vascular and color changes associated with inflammation. Methods: In this cross-sectional study, 40 patients with mild-to-moderate acne vulgaris were enrolled, and 80 dermoscopic images were obtained. Background color, vascular morphology, vascular distribution, and perifollicular yellow halo were analyzed and compared between severity grades (mild vs. moderate) and among lesion types (comedonal, papular, pustular). Results: < 0.05). Conclusion: Progressive deepening of background color and transformation of vascular morphology on dermoscopy are associated with increasing inflammatory activity in acne vulgaris. Quantitative evaluation of these dermoscopic parameters may contribute to preliminary objective severity grading and therapeutic monitoring. Dermoscopy may represent a potentially valuable, noninvasive imaging modality for assessing inflammatory activity in acne.