Predictors of Response to Growth Hormone Therapy in Children with Idiopathic Growth Hormone Deficiency: A Narrative Review
: Growth response to rhGH in IGHD is multifactorial and could be individualized: early identification of suboptimal responders and personalized treatment strategies that integrate clinical, biochemical, and treatment-related data may optimize the final outcome. Future research studies should focus on validated predictive models incorporating genetic and molecular markers.
Authors
- Ignazio Cammisa
- Donato Rigante (ORCID: https://orcid.org/0000-0001-7032-7779)
- Clelia Cipolla
- Eleonora Rulli
- Giulia De Fortuna
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
- Azienda Ospedaliero Universitaria San Giovanni Battista (IT)
Publication Details
- Journal
- Children
- Published
- 2026-04-14
- DOI
- https://doi.org/10.3390/children13040545
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00