Erythema Elevatum Diutinum: An Underdiagnosed EntityA Case Report

Erythema Elevatum Diutinum (EED), an uncommon form of chronic leukocytoclastic vasculitis presents as reddish-brown plaques and papulonodules primarily affecting the extensor surface. It mimics various cutaneous disorders and hence poses diagnostic difficulties. EED is predominantly seen in middle-aged individuals between fourth and sixth decade. EED can also have various extracutaneous manifestations such as arthralgia, scleritis, panuveitis, ulcerative keratitis and neuropathy indicating circulating immune complexes deposition in several organs. Thereby thorough clinical and systemic examination for early diagnosis and comprehensive management of both skin and extracutaneous findings are essential to prevent complications and further progression. The authors hereby report a case of 47-year-old female with long standing diabetes mellitus presenting with asymptomatic papulonodular lesions over the extensor surface with sensory abnormalities, highlighting the diagnostic dilemma and emphasising the importance of histopathological correlation in arriving at appropriate diagnosis.

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Publication Details

Journal
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Published
2026-04-14
DOI
https://doi.org/10.7860/jcdr/2026/84906.23331
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
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article

Erythema Elevatum Diutinum: An Underdiagnosed EntityA Case Report

M Yogalakshmi, S Gayathri, G Sukanya, NR Vignesh
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Autoimmune and Inflammatory Disorders
article

Erythema Elevatum Diutinum: An Underdiagnosed EntityA Case Report

M Yogalakshmi, S Gayathri, G Sukanya, NR Vignesh
article en

Abstract

Erythema Elevatum Diutinum (EED), an uncommon form of chronic leukocytoclastic vasculitis presents as reddish-brown plaques and papulonodules primarily affecting the extensor surface. It mimics various cutaneous disorders and hence poses diagnostic difficulties. EED is predominantly seen in middle-aged individuals between fourth and sixth decade. EED can also have various extracutaneous manifestations such as arthralgia, scleritis, panuveitis, ulcerative keratitis and neuropathy indicating circulating immune complexes deposition in several organs. Thereby thorough clinical and systemic examination for early diagnosis and comprehensive management of both skin and extracutaneous findings are essential to prevent complications and further progression. The authors hereby report a case of 47-year-old female with long standing diabetes mellitus presenting with asymptomatic papulonodular lesions over the extensor surface with sensory abnormalities, highlighting the diagnostic dilemma and emphasising the importance of histopathological correlation in arriving at appropriate diagnosis.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
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Autoimmune and Inflammatory Disorders
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