RNA-Seq Analysis of Human Cumulus Cells Identifies Angiogenic Pathways Associated with Infertility

, showed consistent but non-significant expression trends, suggesting alterations in angiogenesis-related processes within the follicular microenvironment. These findings support the presence of coordinated angiogenesis-related alterations in cumulus cells and provide a basis for future studies exploring their potential relevance in oocyte competence and ART outcomes.

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Publication Details

Journal
Cells
Published
2026-04-11
DOI
https://doi.org/10.3390/cells15080677
Primary Topic
Reproductive Biology and Fertility
Type
article
Field-Weighted Citation Impact
0.00
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article

RNA-Seq Analysis of Human Cumulus Cells Identifies Angiogenic Pathways Associated with Infertility

Alejandro Baratas, Rosario Planelló, Mónica Aquilino, Moisés de la Casa et al.
Cells
Reproductive Biology and Fertility
article

RNA-Seq Analysis of Human Cumulus Cells Identifies Angiogenic Pathways Associated with Infertility

Alejandro Baratas, Rosario Planelló, Mónica Aquilino, Moisés de la Casa, Magdalena Serrano, Rosa Roy, Yosu Franco-Iriarte, Victoria Pérez-Quiroga
article en

Abstract

, showed consistent but non-significant expression trends, suggesting alterations in angiogenesis-related processes within the follicular microenvironment. These findings support the presence of coordinated angiogenesis-related alterations in cumulus cells and provide a basis for future studies exploring their potential relevance in oocyte competence and ART outcomes.

CellsVol. 15(8)
Universidad Nacional de Educación a Distancia (ES), Universidad Rey Juan Carlos (ES), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (ES), Hospital Ruber Internacional (ES), Universidad Autónoma de Madrid (ES), GMV Innovating Solutions (Spain) (ES)
Openalex Percentile: Top 23%
Reproductive Biology and Fertility
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RNA-Seq Analysis of Human Cumulus Cells Identifies Angiogenic Pathways Associated with Infertility — Alejandro Baratas, Rosario Planelló, et al. · Cells (2026) | TGRS Research Map | TGRS