Dynamic changes in brain network functional connectivity following repositioning treatment for benign paroxysmal positional vertigo: an fNIRS study

Objective: To explore the changes in brain network functional connectivity (FC) in patients with benign paroxysmal positional vertigo (BPPV) before and after otoconial repositioning treatment, and to analyze the correlation between FC and the Dizziness Handicap Inventory (DHI) score, thereby elucidating the neural basis of BPPV from a central mechanism perspective. Methods: tests, and correlations were analyzed using Pearson analysis. Results: < 0.01). Conclusion: fNIRS revealed characteristic FC alterations in BPPV: acute-phase decreases, partial sensory cortex recovery post-repositioning, and delayed prefrontal recovery. FC correlated negatively with symptom severity, suggesting its potential as an objective biomarker. These findings provide insights into central mechanisms and support neuroregulation-assisted therapy development.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-04-13
DOI
https://doi.org/10.3389/fneur.2026.1820148
Primary Topic
Vestibular and auditory disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Dynamic changes in brain network functional connectivity following repositioning treatment for benign paroxysmal positional vertigo: an fNIRS study

Qingchun Pan, Renli Huang, Shu Jin, Junhua Xiao
Frontiers in Neurology
Vestibular and auditory disorders
article

Dynamic changes in brain network functional connectivity following repositioning treatment for benign paroxysmal positional vertigo: an fNIRS study

Qingchun Pan, Renli Huang, Shu Jin, Junhua Xiao
article en

Abstract

Objective: To explore the changes in brain network functional connectivity (FC) in patients with benign paroxysmal positional vertigo (BPPV) before and after otoconial repositioning treatment, and to analyze the correlation between FC and the Dizziness Handicap Inventory (DHI) score, thereby elucidating the neural basis of BPPV from a central mechanism perspective. Methods: tests, and correlations were analyzed using Pearson analysis. Results: < 0.01). Conclusion: fNIRS revealed characteristic FC alterations in BPPV: acute-phase decreases, partial sensory cortex recovery post-repositioning, and delayed prefrontal recovery. FC correlated negatively with symptom severity, suggesting its potential as an objective biomarker. These findings provide insights into central mechanisms and support neuroregulation-assisted therapy development.

Frontiers in NeurologyVol. 17
Affiliated Hospital of North Sichuan Medical College (CN)
Good health and well-being
Openalex Percentile: Top 24%
Vestibular and auditory disorders
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Dynamic changes in brain network functional connectivity following repositioning treatment for benign paroxysmal positional vertigo: an fNIRS study — Qingchun Pan, Renli Huang, et al. · Frontiers in Neurology (2026) | TGRS Research Map | TGRS