Dynamic changes in brain network functional connectivity following repositioning treatment for benign paroxysmal positional vertigo: an fNIRS study
Objective: To explore the changes in brain network functional connectivity (FC) in patients with benign paroxysmal positional vertigo (BPPV) before and after otoconial repositioning treatment, and to analyze the correlation between FC and the Dizziness Handicap Inventory (DHI) score, thereby elucidating the neural basis of BPPV from a central mechanism perspective. Methods: tests, and correlations were analyzed using Pearson analysis. Results: < 0.01). Conclusion: fNIRS revealed characteristic FC alterations in BPPV: acute-phase decreases, partial sensory cortex recovery post-repositioning, and delayed prefrontal recovery. FC correlated negatively with symptom severity, suggesting its potential as an objective biomarker. These findings provide insights into central mechanisms and support neuroregulation-assisted therapy development.
Authors
- Qingchun Pan (ORCID: https://orcid.org/0000-0001-8462-3165)
- Renli Huang
- Shu Jin
- Junhua Xiao
Institutions
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-04-13
- DOI
- https://doi.org/10.3389/fneur.2026.1820148
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00