Loading Capsaicin onto Lipid Bilayers: A Molecular Dynamics Study
. Interestingly, when the bilayer was in the gel phase, the ordered lipid was disrupted by the capsaicin. These findings provide valuable insights into the membrane interactions of capsaicin and support the rational design of liposomal delivery systems to enhance its pharmaceutical potential.
Authors
- Jirasak Wong-ekkabut (ORCID: https://orcid.org/0000-0002-3651-9870)
- Nililla Nisoh
- Nathanon Kerdkaen
- Jiramate Kitjanon
- Cristiano L. Dias (ORCID: https://orcid.org/0000-0002-8765-3922)
- Mikko Karttunen (ORCID: https://orcid.org/0000-0002-8626-3033)
Institutions
- New Jersey Institute of Technology (US)
- University of Eastern Finland (FI)
- Kasetsart University (TH)
- Natural Resources Institute Finland (FI)
- Finland University (FI)
- Department of Physics, Mathematics and Informatics (BY)
Publication Details
- Journal
- ACS Omega
- Published
- 2026-04-13
- DOI
- https://doi.org/10.1021/acsomega.5c07901
- Primary Topic
- Lipid Membrane Structure and Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kasetsart University
- National Research Council of Thailand
- Thailand Science Research and Innovation