Immunologic Drivers and Restraints in Colitis-Associated Colorectal Cancer

cytotoxic T lymphocytes, regulatory T cells, and B cells exert divergent effects depending on cytokine milieu, immune context, and disease stage. Understanding immune-cell plasticity and the molecular pathways governing these processes may facilitate the identification of predictive biomarkers and the development of targeted immunomodulatory strategies aimed at preventing CAC.

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Publication Details

Journal
Cancers
Published
2026-04-13
DOI
https://doi.org/10.3390/cancers18081230
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Immunologic Drivers and Restraints in Colitis-Associated Colorectal Cancer

Federica Laudisi, Carmine Stolfi, Rachele Frascatani, Giovanni Monteleone
Cancers
Immune cells in cancer
article

Immunologic Drivers and Restraints in Colitis-Associated Colorectal Cancer

Federica Laudisi, Carmine Stolfi, Rachele Frascatani, Giovanni Monteleone
article en

Abstract

cytotoxic T lymphocytes, regulatory T cells, and B cells exert divergent effects depending on cytokine milieu, immune context, and disease stage. Understanding immune-cell plasticity and the molecular pathways governing these processes may facilitate the identification of predictive biomarkers and the development of targeted immunomodulatory strategies aimed at preventing CAC.

CancersVol. 18(8)
University of Rome Tor Vergata (IT), Policlinico Tor Vergata (IT)
Good health and well-being
Openalex Percentile: Top 27%
Immune cells in cancer
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