The Adjunctive Role of Dynamic Systemic Inflammation-Based Biomarkers in Surgical Risk Stratification of First-Episode Primary Spontaneous Pneumothorax

Dynamic assessment of systemic inflammation-based biomarkers provides clinically relevant insight for surgical risk stratification in first-episode PSP. While baseline measurements alone are insufficient, follow-up values and temporal changes-particularly in CAR, SIII, and NLR-may reflect progression toward a surgical phenotype and could serve as adjunctive, non-directive decision-support indicators in PSP management.