Screening of Ruthenium Complexes as the Protein Light Switches for Protein Detection
for rapid detection of HSA. Notably, this strategy can be extended to screen the β-lactoglobulin light switch that exhibits a 346.1-fold luminescence enhancement. This research provides a universal approach for the discovery of high-performance protein light switches with promising applications in biomedical research and clinical diagnostics.
Authors
- Wei Tantai
- Nian X. Sun (ORCID: https://orcid.org/0000-0002-3120-0094)
- Huan Liu (ORCID: https://orcid.org/0000-0002-0253-647X)
- Chun‐yang Zhang (ORCID: https://orcid.org/0000-0002-8010-1981)
- Zhao-zhao Zhang
- Yan-ni Li
- Qin-feng Xu (ORCID: https://orcid.org/0000-0002-8235-9046)
Institutions
- Shaanxi University of Science and Technology (CN)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2026-04-13
- DOI
- https://doi.org/10.1021/acs.analchem.5c06350
- Primary Topic
- Protein Interaction Studies and Fluorescence Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Education Department of Shaanxi Province
- Department of Human Resources and Social Security of Shaanxi Province