Morphology Control of Phosphorescent CDs@SiO <sub>2</sub> in Aqueous Solution and Application in Liver Cancer Theranostic Drug Delivery
-HA-DOX reduced the viability of HepG2 cells to 22.95%. In vivo studies using tumor-bearing mouse models confirmed a tumor inhibition rate of 75.48%, demonstrating significant antitumor efficacy. This work represents the first successful application of RTP CD composites in drug delivery. The developed system shows great promise as a theranostic candidate for liver cancer by integrating drug delivery and RTP imaging, highlighting its significant potential for cancer therapy applications.
Authors
- Xi Liu (ORCID: https://orcid.org/0000-0002-6741-4094)
- Jinglei Du
- Jie Liu
- Yong Chen
- Yingying Wei
- Shiping Yu
- Jiajia Ren
Institutions
- École Nationale Supérieure de Chimie de Montpellier (FR)
- Interface (United States) (US)
- Sorbonne Université (FR)
- Shanxi Provincial Cancer Hospital (CN)
- École Normale Supérieure (BI)
- Division of Materials Science and Engineering (AU)
- Cancer Hospital of Chinese Academy of Medical Sciences (CN)
- Taiyuan University of Technology (CN)
Publication Details
- Journal
- ACS Applied Bio Materials
- Published
- 2026-04-13
- DOI
- https://doi.org/10.1021/acsabm.5c02420
- Primary Topic
- Carbon and Quantum Dots Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shanxi Scholarship Council of China