Assessment of myocardial fibrosis in ischemic and non-ischemic cardiomyopathies using cardiac magnetic resoance non-contrast T1ρ mapping

Aim: To evaluate the performance of T1ρ mapping for myocardial fibrosis detection across distinct cardiomyopathy entities of ischemic and non-ischemic origin against native T1 mapping. Methods and results: < 0.05). Conclusion: This exploratory study demonstrates the potential of T1ρ mapping as a non-contrast CMR technique for detecting myocardial fibrosis in ischemic and non-ischemic cardiomyopathies. T1ρ showed favorable diagnostic performance compared with native T1 in ICM and HCM with comparable performance in DCM. These findings warrant validation in larger cohorts with diverse cardiac conditions to establish the clinical utility of T1ρ imaging.