TAX1BP1 targets STING1 via microautophagy and Golgiphagy to limit inflammatory signaling
: cGAMP: cyclic guanosine monophosphate-adenosine monophosphate; CGAS: Cyclic GMP-AMP synthase; ER: endoplasmic reticulum; ESCRT: endosomal sorting complex required for transport; ECTV: ectromelia virus; HGS: hepatocyte growth factor-regulated tyrosine kinase substrate; IKK: IκB kinase; IRF3: interferon regulatory factor 3; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; SQSTM1: sequestosome 1; STING1: stimulator of interferon response cGAMP interactor 1; TBK1: TANK binding kinase 1; TAX1BP1: Tax1 binding protein 1.
Authors
- Edward W. Harhaj (ORCID: https://orcid.org/0000-0003-1197-6765)
- Sujit Suklabaidya (ORCID: https://orcid.org/0000-0002-6460-6410)
- Suchitra Mohanty
Institutions
- William Penn University (US)
- California University of Pennsylvania (US)
Publication Details
- Journal
- Autophagy
- Published
- 2026-04-13
- DOI
- https://doi.org/10.1080/15548627.2026.2658230
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Allergy and Infectious Diseases