Development of a Human IgG1 Monoclonal Antibody Targeting Transferrin Receptor 1 for Antitumor Drug Delivery
: These findings indicate that T8IgG1 is a moderate-affinity, internalizing anti-TfR1 antibody and highlight its potential as a promising candidate for TfR1-based targeted antitumor drug delivery systems.
Authors
- Minghui Yan (ORCID: https://orcid.org/0000-0002-9628-4938)
- Zhaoyun Zong
- Tingting Ji
- Ningyuan Gong
- Shiyu Chen
Institutions
- Nanjing University of Chinese Medicine (CN)
- Chinese Academy of Sciences (CN)
- Shanghai Institute of Materia Medica (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Antibodies
- Published
- 2026-04-13
- DOI
- https://doi.org/10.3390/antib15020034
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China