Medical Question Answering System Based on Retrieval-augmented Generation

This study investigates the feasibility and reliability of Retrieval-Augmented Generation (RAG) in medical question-answering tasks. To address issues such as hallucination and lack of traceability in large language models (LLMs) in medical contexts, a medical knowledge base was constructed using the cancer-related subset of a Kaggle healthcare dataset. Experiments were conducted with the Qwen-Plus and Qwen-Flash models. Evaluation was carried out across three dimensions: answer accuracy, source traceability, and refusal capability, with additional analysis on the impact of different retrieval quantities (top-k) on performance. The results show that RAG significantly improves the semantic consistency of model responses, outperforming the baseline model on the BERTScore F1 metric. It also demonstrates strong performance in terms of refusal rate and attribution accuracy, highlighting its advantages in mitigating hallucinations and enhancing interpretability. Furthermore, the findings indicate that a retrieval quantity of k=5 yields the best overall performance. This study validates the potential of RAG in medical question answering and provides empirical support for building trustworthy medical AI systems.

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Publication Details

Journal
Springer Link (Chiba Institute of Technology)
Published
2026-04-06
DOI
https://doi.org/10.1051/itmconf/20268401001/pdf
Primary Topic
Topic Modeling
Type
article
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article

Medical Question Answering System Based on Retrieval-augmented Generation

Chengwei Cao
Springer Link (Chiba Institute of Technology)
Topic Modeling
article

Medical Question Answering System Based on Retrieval-augmented Generation

Chengwei Cao
article en

Abstract

This study investigates the feasibility and reliability of Retrieval-Augmented Generation (RAG) in medical question-answering tasks. To address issues such as hallucination and lack of traceability in large language models (LLMs) in medical contexts, a medical knowledge base was constructed using the cancer-related subset of a Kaggle healthcare dataset. Experiments were conducted with the Qwen-Plus and Qwen-Flash models. Evaluation was carried out across three dimensions: answer accuracy, source traceability, and refusal capability, with additional analysis on the impact of different retrieval quantities (top-k) on performance. The results show that RAG significantly improves the semantic consistency of model responses, outperforming the baseline model on the BERTScore F1 metric. It also demonstrates strong performance in terms of refusal rate and attribution accuracy, highlighting its advantages in mitigating hallucinations and enhancing interpretability. Furthermore, the findings indicate that a retrieval quantity of k=5 yields the best overall performance. This study validates the potential of RAG in medical question answering and provides empirical support for building trustworthy medical AI systems.

Springer Link (Chiba Institute of Technology)
Quality Education
Openalex Percentile: Top 17%
Topic Modeling
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Medical Question Answering System Based on Retrieval-augmented Generation — Chengwei Cao · Springer Link (Chiba Institute of Technology) (2026) | TGRS Research Map | TGRS