Genome-Wide CRISPR/Cas9 Screening Reveals <i>BmM-ALP</i> Orchestrates the Antioxidant Response and Metabolic Adaptations for Heat Resistance in <i>Bombyx mori</i>
to Vitamin B1 metabolism, illustrating a novel connection between energy homeostasis and thermal adaptation. The findings provide new insights that can be applied to breeding resistant strains in agriculture and biodiversity conservation in the context of global warming.
Authors
- Z. H. Liu
- Minhui Pan
- Xinyue Jia
- Wending Xiao
- Zhanqi Dong
- Cheng Lu
- Zihan Peng
- Siyi Wei
- Hai Hu
Institutions
- Southwest University (CN)
- Ministry of Agriculture (EE)
- Ministry of Agriculture (CA)
- Sericultural Research Institute (CN)
- Sichuan Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- ACS Synthetic Biology
- Published
- 2026-04-13
- DOI
- https://doi.org/10.1021/acssynbio.6c00053
- Primary Topic
- Physiological and biochemical adaptations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Agricultural Research System
- National Key Research and Development Program of China