Assessment of Bronchodilator Responsiveness and Spirometric Patterns in Patients with Rhinitis and Suspected Asthma

Background: Bronchodilation testing (BDT) is routinely used to assess reversibility of airflow limitation. For patients with rhinitis who report asthma-related symptoms but often show preserved spirometry, the clinical patterns associated with bronchodilator responsiveness (BDR) are less clearly described. Understanding these patterns may help clinicians interpret lung function in real-world practice. Methods: improvements below the conventional ≥12% criterion and asthma-related symptoms. Results: improvements slightly below the conventional ≥12% bronchodilator threshold were also associated with asthma-related symptoms, although these findings were exploratory and not intended as diagnostic criteria. Conclusion: changes may be clinically relevant and warrant further prospective study. These findings may help clinicians judge when bronchodilation testing is informative during the routine evaluation of suspected airway disease.

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Publication Details

Journal
Journal of Asthma and Allergy
Published
2026-04-01
DOI
https://doi.org/10.2147/jaa.s589700
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Assessment of Bronchodilator Responsiveness and Spirometric Patterns in Patients with Rhinitis and Suspected Asthma

Zhouxian Pan, Xinyu Liu, Jia Yin, Xin Li et al.
Journal of Asthma and Allergy
Asthma and respiratory diseases
article

Assessment of Bronchodilator Responsiveness and Spirometric Patterns in Patients with Rhinitis and Suspected Asthma

Zhouxian Pan, Xinyu Liu, Jia Yin, Xin Li, Kai Guan
article en

Abstract

Background: Bronchodilation testing (BDT) is routinely used to assess reversibility of airflow limitation. For patients with rhinitis who report asthma-related symptoms but often show preserved spirometry, the clinical patterns associated with bronchodilator responsiveness (BDR) are less clearly described. Understanding these patterns may help clinicians interpret lung function in real-world practice. Methods: improvements below the conventional ≥12% criterion and asthma-related symptoms. Results: improvements slightly below the conventional ≥12% bronchodilator threshold were also associated with asthma-related symptoms, although these findings were exploratory and not intended as diagnostic criteria. Conclusion: changes may be clinically relevant and warrant further prospective study. These findings may help clinicians judge when bronchodilation testing is informative during the routine evaluation of suspected airway disease.

Journal of Asthma and AllergyVol. Volume 19
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Peking Union Medical College Hospital, Peking Union Medical College
Good health and well-being
Openalex Percentile: Top 21%
Asthma and respiratory diseases
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