Synthesis of Unsymmetrical Carbazoles: A Mechanistic Cautionary Tale When Using <i>ortho</i> -Borylaryl Triflates in Catalysis
-borylaryl triflates, which is in contrast to previous reports which invoke them as aryne precursors. Utilizing Hammett parameters as a rationale, we developed a predictive approach to optimize the placement of substituents on the starting materials to maximize yields.
Authors
- Courtney C. Roberts (ORCID: https://orcid.org/0000-0001-8177-4013)
- Douglas Kavaguti
- Brylon N. Denman
Institutions
- University of Minnesota System (US)
Publication Details
- Journal
- ACS Catalysis
- Published
- 2026-04-13
- DOI
- https://doi.org/10.1021/acscatal.6c01835
- Primary Topic
- Organoboron and organosilicon chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alfred P. Sloan Foundation
- Bristol-Myers Squibb Foundation
- Camille and Henry Dreyfus Foundation
- Amgen
- University of Minnesota
- National Institute of General Medical Sciences