SkinSenseAI: AI-Driven Skin Disease Detection with Retrieval-Augmented Clinical Decision Support

Skin diseases are a widespread health concern, and delayed diagnosis often occurs due to limited access to dermatologists or lack of awareness. While deep learning models can detect skin conditions from images, many operate as “black boxes” without clear explanations, and standalone Large Language Models (LLMs) may produce inaccurate medical information. This paper presents SkinSense AI, an intelligent skin health assistant that combines image-based disease detection with Retrieval-Augmented Generation (RAG) to deliver accurate and explainable results. A CNN model identifies possible conditions from skin images, while the RAG system retrieves trusted medical knowledge to generate clear, evidence-based explanations, prevention tips, and lifestyle guidance. The platform also includes a questionnaire-based chatbot and a severity scoring module for early screening and triage. Results show that integrating computer vision with RAG improves both diagnostic reliability and user understanding. SkinSense AI serves as a scalable early-awareness tool that supports informed decision-making and encourages timely professional consultation.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-04-13
DOI
https://doi.org/10.5281/zenodo.19553490
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
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article

SkinSenseAI: AI-Driven Skin Disease Detection with Retrieval-Augmented Clinical Decision Support

Girish Patil, Sanika Kharat, Dr.Rajashree Thosar, Sakshi Khangar et al.
Zenodo (CERN European Organization for Nuclear Research)
Cutaneous Melanoma Detection and Management
article

SkinSenseAI: AI-Driven Skin Disease Detection with Retrieval-Augmented Clinical Decision Support

Girish Patil, Sanika Kharat, Dr.Rajashree Thosar, Sakshi Khangar, Nihir Borkar, Renuka Vakhare, Dr. Devidas Thosar
article en

Abstract

Skin diseases are a widespread health concern, and delayed diagnosis often occurs due to limited access to dermatologists or lack of awareness. While deep learning models can detect skin conditions from images, many operate as “black boxes” without clear explanations, and standalone Large Language Models (LLMs) may produce inaccurate medical information. This paper presents SkinSense AI, an intelligent skin health assistant that combines image-based disease detection with Retrieval-Augmented Generation (RAG) to deliver accurate and explainable results. A CNN model identifies possible conditions from skin images, while the RAG system retrieves trusted medical knowledge to generate clear, evidence-based explanations, prevention tips, and lifestyle guidance. The platform also includes a questionnaire-based chatbot and a severity scoring module for early screening and triage. Results show that integrating computer vision with RAG improves both diagnostic reliability and user understanding. SkinSense AI serves as a scalable early-awareness tool that supports informed decision-making and encourages timely professional consultation.

Zenodo (CERN European Organization for Nuclear Research)
Peace, Justice and strong institutions
Openalex Percentile: Top 6%
Cutaneous Melanoma Detection and Management
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