Diagnostic Accuracy of MMPs for Predicting Hemorrhagic Transformation After Ischemic Stroke

Ischemic stroke, primarily caused by cerebral artery occlusion, is a leading cause of death and disability. Hemorrhagic transformation (HT) is a known complication that worsens outcomes. Matrix metalloproteinases (MMPs), especially MMP-9, are implicated in neuroinflammation and blood-brain barrier (BBB) disruption after stroke. This study investigates the association between MMP levels and HT events.

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Publication Details

Journal
Neurology Open Access
Published
2026-04-13
DOI
https://doi.org/10.1212/wn9.0000000000000073
Primary Topic
Protease and Inhibitor Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic Accuracy of MMPs for Predicting Hemorrhagic Transformation After Ischemic Stroke

Anas Elgenidy, Ahmad Abdulrahman Alkasem, Bassel Alrabadi, Esraa Mohammed et al.
Neurology Open Access
Protease and Inhibitor Mechanisms
article

Diagnostic Accuracy of MMPs for Predicting Hemorrhagic Transformation After Ischemic Stroke

Anas Elgenidy, Ahmad Abdulrahman Alkasem, Bassel Alrabadi, Esraa Mohammed, Elsayed Kshk
article en

Abstract

Ischemic stroke, primarily caused by cerebral artery occlusion, is a leading cause of death and disability. Hemorrhagic transformation (HT) is a known complication that worsens outcomes. Matrix metalloproteinases (MMPs), especially MMP-9, are implicated in neuroinflammation and blood-brain barrier (BBB) disruption after stroke. This study investigates the association between MMP levels and HT events.

Neurology Open AccessVol. 2(2)
Jordan University of Science and Technology (JO), Damanhour University (EG), Mutah University (JO), Jacksonville College (US), Minia University Hospital (EG), Minia University (EG)
Openalex Percentile: Top 16%
Protease and Inhibitor Mechanisms
DOIOpen Access PDFOpenAlex
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Diagnostic Accuracy of MMPs for Predicting Hemorrhagic Transformation After Ischemic Stroke — Anas Elgenidy, Ahmad Abdulrahman Alkasem, et al. · Neurology Open Access (2026) | TGRS Research Map | TGRS