Prophage-mediated lysogenic conversion drives virulence evolution and genomic plasticity in <i>Streptococcus suis</i> serotype 9
. The discovery of a "one strain, multiple sources" acquisition pattern and the "gene prison" model explains how virulence traits can be stably maintained and disseminated. These findings redefine prophages as dual drivers of bacterial evolution, providing new insights for surveillance and intervention strategies in the swine industry.
Authors
- Yuyu Guo (ORCID: https://orcid.org/0000-0002-9919-9894)
- Rui Tang (ORCID: https://orcid.org/0000-0002-9313-0802)
- Yuwan Li (ORCID: https://orcid.org/0000-0001-8959-6805)
- Yan Liang (ORCID: https://orcid.org/0000-0001-6290-5540)
- Yonggang Qu
- Kexun Lian
- Zhenglong Wen
- Shoupan Li
Institutions
- Shihezi University (CN)
- Animal Husbandry & Veterinary (IN)
- Tebian Electric Apparatus (China) (CN)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2026-04-13
- DOI
- https://doi.org/10.1128/spectrum.00061-26
- Primary Topic
- Streptococcal Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00