Furo‐/Thieno[2,3‐ <i>c</i> ]pyridine Derivatives: Synthesis, Reactions, and Applications

Furo‐/thienopyridines constitute a class of heterocyclic compounds that have garnered significant attention in medicinal chemistry due to their diverse biological activities and potential therapeutic applications. These compounds represent a versatile class that, in addition to their importance in medicinal chemistry, also have significant implications in materials science. Ongoing research into their synthesis and functionalization is essential for unlocking their full potential. This review features synthetic approaches to the preparation of furo‐/thienopyridines published from 2008 until 2025, with a primary focus on the [2,3‐ c ] fusion. Older reports will be mentioned where appropriate for comparison. The characteristics and applications of the described compounds are discussed and summarized in tables.

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Publication Details

Journal
European Journal of Organic Chemistry
Published
2026-04-12
DOI
https://doi.org/10.1002/ejoc.70418
Primary Topic
Synthesis and Reactivity of Heterocycles
Type
article
Field-Weighted Citation Impact
0.00
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article

Furo‐/Thieno[2,3‐ c ]pyridine Derivatives: Synthesis, Reactions, and Applications

Ömer Tahir Günkara, Kumsal Eroğlu, Yulia Ivanova
European Journal of Organic Chemistry
Synthesis and Reactivity of Heterocycles
article

Furo‐/Thieno[2,3‐ c ]pyridine Derivatives: Synthesis, Reactions, and Applications

Ömer Tahir Günkara, Kumsal Eroğlu, Yulia Ivanova
article en

Abstract

Furo‐/thienopyridines constitute a class of heterocyclic compounds that have garnered significant attention in medicinal chemistry due to their diverse biological activities and potential therapeutic applications. These compounds represent a versatile class that, in addition to their importance in medicinal chemistry, also have significant implications in materials science. Ongoing research into their synthesis and functionalization is essential for unlocking their full potential. This review features synthetic approaches to the preparation of furo‐/thienopyridines published from 2008 until 2025, with a primary focus on the [2,3‐ c ] fusion. Older reports will be mentioned where appropriate for comparison. The characteristics and applications of the described compounds are discussed and summarized in tables.

European Journal of Organic ChemistryVol. 29(17)
Istanbul Technical University (TR), KU Leuven (BE)
Openalex Percentile: Top 29%
Synthesis and Reactivity of Heterocycles
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